Bringing FLASH to the Clinic: Treatment Planning Considerations for Ultrahigh Dose-Rate Proton Beams

Volume: 106, Issue: 3, Pages: 621 - 629
Published: Mar 1, 2020
Abstract
Purpose Preclinical research into ultrahigh dose rate (eg, ≥40 Gy/s) “FLASH”-radiation therapy suggests a decrease in side effects compared with conventional irradiation while maintaining tumor control. When FLASH is delivered using a scanning proton beam, tissue becomes subject to a spatially dependent range of dose rates. This study systematically investigates dose rate distributions and delivery times for proton FLASH plans using stereotactic...
Paper Details
Title
Bringing FLASH to the Clinic: Treatment Planning Considerations for Ultrahigh Dose-Rate Proton Beams
Published Date
Mar 1, 2020
Volume
106
Issue
3
Pages
621 - 629
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