Electrospinning of biocompatible alginate-based nanofiber membranes via tailoring chain flexibility

Electrospinning of pure alginate or derivatives has always been a pursuing goal in biological fields in recent years owing to its fascinating biological characteristics and biomimetic structures. Yet it is still a severe challenge in view of its insufficient entanglements and strong electrostatic repulsions. Herein, alginate dialdehyde (ADA) with improved and adjustable chain flexibility was prepared via periodate-oxidation. Chain flexibility,...