Next‐generation sequencing in salivary gland carcinoma: Targetable alterations lead to a therapeutic advantage—Multicenter experience

Volume: 42, Issue: 4, Pages: 599 - 607
Published: Apr 1, 2020
Abstract
Salivary gland cancers (SGCs) are rare. The approach to metastatic patients is histology-dependent. There is little evidence on whether next-generation sequencing (NGS) findings translate to tumor control in SGCs.We analyzed all patients with histologically confirmed SGC who underwent NGS.Twenty-seven patients were identified, 14 (51.8%) had targetable findings in NGS: 5 ERBB2 amplifications, 3 PIK3CA mutations, 2 RUNX1 mutations, 1 TRIM33-RET...
Paper Details
Title
Next‐generation sequencing in salivary gland carcinoma: Targetable alterations lead to a therapeutic advantage—Multicenter experience
Published Date
Apr 1, 2020
Volume
42
Issue
4
Pages
599 - 607
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