Chemical profiles and screening of potential α-glucosidase inhibitors from Sichuan pepper using ultra-filtration combined with UHPLC-Q-TOF

Sichuan pepper, commonly used as a food seasoning, possesses unique anti-diabetic properties. This study uses ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (UHPLC-Q-TOF) to elucidate the chemical profile of Sichuan pepper. Further, an ultra-filtration was coupled with UHPLC-Q-TOF to screen the α-glucosidase inhibitors (AGIs) for the first time. Results confirmed significant variation...