Solid-Supported Proteins in the Liquid Chromatography Domain to Probe Ligand-Target Interactions
Abstract
Ligand-target interactions play a central role in drug discovery processes because these interactions are crucial in biological systems. Small molecules-proteins interactions can regulate and modulate protein function and activity through conformational changes. Therefore, bioanalytical tools to screen new ligands have focused mainly on probing ligand-target interactions. These interactions have been evaluated by using solid-supported proteins,...
Paper Details
Title
Solid-Supported Proteins in the Liquid Chromatography Domain to Probe Ligand-Target Interactions
Published Date
Nov 15, 2019
Journal
Volume
7
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