Making a three-way contact

Cell Biology Membrane contact sites between organelles are important in several cellular functions. Within cells, lipids are stored in specialized organelles known as lipid droplets. In some cell types, lipid droplets interact directly with mitochondria. In adipocytes, which are professional fat-storing cells, Freyre et al. found that the outer mitochondrial membrane protein MIGA2 tethers mitochondria to lipid droplets. They identified a lipid...