Characterisation of a New Human Alveolar Macrophage-Like Cell Line (Daisy)

Published on Nov 16, 2019in Lung1.817
· DOI :10.1007/S00408-019-00288-3
Laura R. Sadofsky12
Estimated H-index: 12
(Hull York Medical School),
Yvette A. Hayman3
Estimated H-index: 3
(Hull York Medical School)
+ 6 AuthorsAlyn H. Morice2
Estimated H-index: 2
(Hull York Medical School)
Sources
Abstract
Purpose There is currently no true macrophage cell line and in vitro experiments requiring these cells currently require mitogenic stimulation of a macrophage precursor cell line (THP-1) or ex vivo maturation of circulating primary monocytes. In this study, we characterise a human macrophage cell line, derived from THP-1 cells, and compare its phenotype to the THP-1 cells.
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