Leukemic Cell with a Novel Kinase Fusion Gene SPAG9-JAK2 Exhibits High Sensitivity to Ruxolitinib
Abstract
[Background and aim of this study] Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a distinct subtype of B-ALL with poor prognosis. JAK2 related fusion genes with diverse partner genes have been identified in this subtype, especially in adolescent and young adults (AYA). Previously, we identified SPAG9-JAK2 fusion gene in 14-year-old boy with Ph-like ALL (Kawamura M, et al. Genes Chromosomes Cancer. 2015). JAK2 fusion...
Paper Details
Title
Leukemic Cell with a Novel Kinase Fusion Gene SPAG9-JAK2 Exhibits High Sensitivity to Ruxolitinib
Published Date
Nov 13, 2019
Journal
Volume
134
Issue
Supplement_1
Pages
5044 - 5044
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Notes
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