Review paper

Specialized pro-resolving lipid mediators: A new class of non-immunosuppressive and non-opioid analgesic drugs

Volume: 151, Pages: 104549 - 104549
Published: Jan 1, 2020
Abstract
We now appreciate that the mechanism of resolution depends on an active and time-dependent biosynthetic shift from pro-inflammatory to pro-resolution mediators, the so-called specialized pro-resolving lipid mediators (SPMs). These SPMs are biosynthesized from the omega-3 fatty acids arachidonic acid (AA), eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), or docosahexaenoic acid (DHA). Despite effective for a fraction of patients with...
Paper Details
Title
Specialized pro-resolving lipid mediators: A new class of non-immunosuppressive and non-opioid analgesic drugs
Published Date
Jan 1, 2020
Volume
151
Pages
104549 - 104549
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