Melatonin promotes the development of immature oocytes from the COH cycle into healthy offspring by protecting mitochondrial function
Abstract
Melatonin (MT) regulates reproductive performance as a potent antioxidant; however, its beneficial effects on oocyte development remain largely unknown, especially in human oocytes. The collected 193 immature oocytes from the controlled ovarian hyperstimulation (COH) cycle underwent in vitro maturation (IVM) in IVM medium contained 10 μmol/L MT (n = 105, M group) and no MT (n = 88, NM group), followed by insemination and embryo culture. The...
Paper Details
Title
Melatonin promotes the development of immature oocytes from the COH cycle into healthy offspring by protecting mitochondrial function
Published Date
Nov 28, 2019
Journal
Volume
68
Issue
1
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