Retrospective determination of regenerated nerve agent sarin in human blood by liquid chromatography–mass spectrometry and in vivo implementation in rabbit
Abstract
The highly toxic nerve agent sarin (o-isopropyl methyl-phosphonofluoridate, GB) has been used in several armed conflicts and terror attacks in recent decades. Due to its inherent high sensitivity, liquid chromatography–mass spectrometry (LC–MS/MS) has the potential to detect ultratrace levels of fluoride-regenerated G and V agents after appropriate chemical derivatization. A new method for the retrospective determination of exposure to sarin was...
Paper Details
Title
Retrospective determination of regenerated nerve agent sarin in human blood by liquid chromatography–mass spectrometry and in vivo implementation in rabbit
Published Date
Nov 13, 2019
Journal
Volume
94
Issue
1
Pages
103 - 111
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