Optimization of process variables using response surface methodology for tocopherol extraction from Roselle seed oil by supercritical carbon dioxide

Hibiscus sabdariffa L. (Roselle) seeds are rich in proteins, carbohydrates and unsaturated fatty acids, and are a good source of minerals and antioxidants. Supercritical carbon dioxide (SC-CO2) extraction was applied for extraction of oil from Roselle seed at temperatures of 40 °C to 80 °C and pressures of 20 MPa to 30 MPa. The effects of temperature and pressure on the extraction yield and solubility of oil were determined. Process optimization...