Preparation of a stilbene diamido-bridged bis(β-cyclodextrin)-bonded chiral stationary phase for enantioseparations of drugs and pesticides by high performance liquid chromatography

A stilbene diamido-bridged bis(β-cyclodextrin) was synthesized via the reaction between 4,4′-stilbene dicarboxylic acid and 6-deoxy-6-amino-β-cyclodextrin. Then it was bonded onto the surface of an ordered mesoporous SBA-15 to obtain a novel bridged bis(β-cyclodextrin)-bonded chiral stationary phase (SBCDP). The structures of the bridged bis(β-cyclodextrin) and SBCDP were characterized by the mass spectrometry, nuclear magnetic resonance,...