MAGE-A1 in lung adenocarcinoma as a promising target of chimeric antigen receptor T cells.
Abstract
Cancer/testis antigens (CTAs) are a special type of tumor antigen and are believed to act as potential targets for cancer immunotherapy. In this study, we first screened a rational CTA MAGE-A1 for lung adenocarcinoma (LUAD) and explored the detailed characteristics of MAGE-A1 in LUAD development through a series of phenotypic experiments. Then, we developed a novel MAGE-A1-CAR-T cell (mCART) using lentiviral vector based on our previous...
Paper Details
Title
MAGE-A1 in lung adenocarcinoma as a promising target of chimeric antigen receptor T cells.
Published Date
Oct 22, 2019
Volume
12
Issue
1
Pages
106 - 106
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History