De novo compartment deconvolution and weight estimation of tumor samples using DECODER
Abstract
Tumors are mixtures of different compartments. While global gene expression analysis profiles the average expression of all compartments in a sample, identifying the specific contribution of each compartment remains a challenge. With the increasing recognition of the importance of non-neoplastic components, the ability to breakdown the gene expression contribution of each is critical. Here, we develop DECODER, an integrated framework which...
Paper Details
Title
De novo compartment deconvolution and weight estimation of tumor samples using DECODER
Published Date
Oct 18, 2019
Journal
Volume
10
Issue
1
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