Regulation of calpain 2 expression by miR-223 and miR-145

Volume: 1862, Issue: 10, Pages: 194438 - 194438
Published: Oct 1, 2019
Abstract
Calpain 2 (CAPN2) is a Ca2+-dependent cysteine-protease that is involved in different cellular processes. Despite its important role, little is known about how CAPN2 expression is regulated. This study addressed the potential regulation of CAPN2 by microRNAs (miRNAs) in human endothelial cells. Two miRNAs were found to regulate CAPN2 expression by two distinct mechanisms, one direct and the other indirect. MiR-223 directly targeted CAPN2 by...
Paper Details
Title
Regulation of calpain 2 expression by miR-223 and miR-145
Published Date
Oct 1, 2019
Journal
Volume
1862
Issue
10
Pages
194438 - 194438
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