Fast and Efficient Fc-Specific Photoaffinity Labeling To Produce Antibody–DNA Conjugates
Abstract
Antibody-DNA conjugates are powerful tools for DNA-assisted protein analysis. Growing usage of these methods demands efficient production of high-quality conjugates. We developed an easy and fast synthesis route yielding covalent antibody-DNA conjugates with a defined conjugation site and low batch-to-batch variability. We utilize the Z domain from protein A, containing the unnatural amino acid 4-benzoylphenylalanine (BPA) for photoaffinity...
Paper Details
Title
Fast and Efficient Fc-Specific Photoaffinity Labeling To Produce Antibody–DNA Conjugates
Published Date
Oct 14, 2019
Journal
Volume
30
Issue
11
Pages
2790 - 2798
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