Sirt6 attenuates hypoxia‐induced tubular epithelial cell injury via targeting G2/M phase arrest

Acute kidney injury (AKI) is a condition that has a high incidence and death rate. Unfortunately, the kidney may not recover completely after AKI, which then develops to chronic kidney disease (CKD). Therefore, it is necessary to identify potential curative targets to avoid its development to CKD. As an NAD + ‐dependent deacetylase, sirtuin 6 (Sirt6) has been linked to different types of biological processes. In the present work, our group...