Redox-Mediated Mechanism of Chemoresistance in Cancer Cells.
Abstract
Cellular reactive oxygen species (ROS) status is stabilized by a balance of ROS generation and elimination called redox homeostasis. ROS is increased by activation of endoplasmic reticulum stress, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase family members and adenosine triphosphate (ATP) synthesis of mitochondria. Increased ROS is detoxified by superoxide dismutase, catalase, and peroxiredoxins. ROS has a role as a secondary...
Paper Details
Title
Redox-Mediated Mechanism of Chemoresistance in Cancer Cells.
Published Date
Oct 10, 2019
Journal
Volume
8
Issue
10
Pages
471
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