Directed Copper-Catalyzed Intermolecular Aminative Difunctionalization of Unactivated Alkenes

A diverse collection of copper-catalyzed intermolecular aminative difunctionalizations of unactivated alkenes with N-halodialkylamines as the terminal dialkylamino source is reported. A bidentate auxiliary tethered on the alkene substrates is crucial, which can promote the migratory insertion of nonactivated alkenes into the aminyl radical–metal complex and stabilize the resultant high-valent copper intermediate to allow for further...