Genomic alterations predict clinical response to systemic chemotherapy and immune checkpoint blockade in biliary tract cancer

Background null Previous studies have identified several targetable oncogenic mutations in biliary tract cancer (BTC). However, reliable predictors of clinical response to therapeutic agents have not been established. This study aimed to identify predictors of clinical response to chemotherapy and immune checkpoint blockade in advanced BTC patients. null null null Methods null Genomic alterations in 54 patients with recurrent or metastatic BTC...