Crohn’s Disease Connectome Conundrums: Relevance to the Prevalence and Management of Mood Disorders

Thomann AK, Reindl W, Wüstenberg T, et al. Aberrant brain structural large-scale connectome in Crohn’s disease. Neurogastroenterol Motil 2019;31:e13593. Brain magnetic resonance imaging (MRI) has identified multifocal cerebral changes in patients with Crohn’s disease (CD), suggesting that central processing may be impaired in these patients (J Crohn’s Colitis 2015;9:532-540). Despite this, the concept of regional specialization fails to account...