Transcatheter closure of patent foramen ovale in patients older than 60 years of age with cryptogenic embolism

Randomized trials have shown the efficacy of transcatheter closure of patent foramen ovale (PFO) in patients aged ≤ 60 years with cryptogenic embolism. We aimed to assess the long-term safety and efficacy of PFO closure in patients aged > 60 years. Of 475 consecutive patients with cryptogenic embolism who underwent PFO closure, 90 older patients aged > 60 years (mean, 66 ± 5 years) were compared with 385 younger patients aged ≤ 60 years (mean,...