Antibody

Onchocerciasis

Strongyloides stercoralis

Serology

Helminths

Ivermectin

Strongyloidiasis

Internal medicine

Clinical endpoint

Veterinary medicine

Surgery

Randomized controlled trial

Immunology

Medicine

The Lancet Infectious Diseases

Multiple doses of ivermectin did not show higher efficacy and was tolerated less than a single dose. A single dose should therefore be preferred for the treatment of non-disseminated strongyloidiasis.

Multiple-dose versus single-dose ivermectin for Strongyloides stercoralis infection (Strong Treat 1 to 4): a multicentre, open-label, phase 3, randomised controlled superiority trial