Perspective: Clinical relevance of the dichotomous classification of Alzheimer's disease biomarkers: Should there be a “gray zone”?
Volume: 15, Issue: 10, Pages: 1348 - 1356
Published: Sep 26, 2019
Abstract
The 2018 National Institute on Aging and the Alzheimer's Association (NIA‐AA) research framework recently redefined Alzheimer's disease (AD) as a biological construct, based on in vivo biomarkers reflecting key neuropathologic features. Combinations of normal/abnormal levels of three biomarker categories, based on single thresholds, form the AD signature profile that defines the biological disease state as a continuum, independent of clinical...
Paper Details
Title
Perspective: Clinical relevance of the dichotomous classification of Alzheimer's disease biomarkers: Should there be a “gray zone”?
Published Date
Sep 26, 2019
Volume
15
Issue
10
Pages
1348 - 1356
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