DCLK1 integrates induction of TRIB3, EMT, drug resistance and poor prognosis in colorectal cancer

Volume: 41, Issue: 3, Pages: 303 - 312
Published: Sep 28, 2019
Abstract
Doublecortin-like kinase 1 (DCLK1) promotes tumour proliferation in human colorectal cancer (CRC). To elucidate the mechanism and clinical relevance of this association, we performed expression analysis using commercially available colon carcinoma cell lines (SW480, HCT116, CaCO2, SW48 and SKCO1) and immunohistochemical analysis of 200 resected CRC samples for correlation with clinical features. DCLK1 showed a high level of expression,...
Paper Details
Title
DCLK1 integrates induction of TRIB3, EMT, drug resistance and poor prognosis in colorectal cancer
Published Date
Sep 28, 2019
Volume
41
Issue
3
Pages
303 - 312
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