Effect of If Current Blockade on Newborn Rat Heart Isolated According to Langendorff.

Volume: 167, Issue: 4, Pages: 424 - 427
Published: Aug 1, 2019
Abstract
The study examined the effects of hyperpolarization-activated funny current (If) on HR and coronary flow in Langendorff-isolated hearts from newborn rats. Blockade of If current with ZD7288 changed the examined cardiac parameters. The blocker in a concentration of 10-9 M decreased HR by 26.8% (p≤0.05). In concentrations 10-8, 10-7, 10-6, and 10-5 M ZD7288 produced minor differently directed effects. In a concentration of 10-5 M, ZD7288 reduced...
Paper Details
Title
Effect of If Current Blockade on Newborn Rat Heart Isolated According to Langendorff.
Published Date
Aug 1, 2019
Volume
167
Issue
4
Pages
424 - 427
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