Functional perfusion image guided radiation treatment planning for locally advanced lung cancer

Functional avoidance radiation therapy (RT) aims at sparing functional lung regions. The purpose of this simulation study was to evaluate the feasibility of functional lung avoidance methodology in RT of lung cancer and to characterize the achievable dosimetry of single photon emission computed tomography (SPECT) guided treatment planning.Fifteen consecutive lung cancer patients were included and planned for definitive RT of 60-66 Gy in 2-Gy...