Longitudinal Analysis of Depression and Anxiety Symptoms as Independent Predictors of Neurocognitive Function: Prospective Trial of Brain Tumor Patients Receiving Radiotherapy [RT]

Brain tumor patients commonly experience depression and anxiety. In other neurologic conditions (e.g. Huntington’s) these symptoms are associated with neurocognitive decline. Since neurocognitive function is a critical outcome for brain tumor patients, we hypothesized that increased depression and anxiety symptoms will be independently associated with worsened neurocognition after brain RT. On a prospective trial, 54 primary brain tumor patients...