Automated measurement of neutrophil CD64 expression for diagnosing sepsis in critically ill patients

Although early identification of sepsis improves outcome, prompt and correct diagnostic remains often challenging. The expression of the high affinity immunoglobulin-Fc fragment receptor I CD64 on neutrophils is upregulated during acute inflammation. We here aimed at determining the usefulness of its rapid measurement in diagnosing sepsis.Seventy-two consecutive patients were enrolled upon admission to Intensive Care Unit within a two-month...