Pathology

Cell

Neuroscience

Neovascularization

Disease

Sprouting angiogenesis

Biology

Cancer

Endothelial stem cell

Cell type

Metabolic pathway

In vitro

Angiogenesis

Metabolism

Signal transduction

Cell biology

Cell metabolism

Cancer research

Genetics

Biochemistry

Medicine

Cancer cell

Cell Metabolism

Angiogenesis research has been focused for decades on growth factors and has largely overlooked the role of endothelial cell metabolism. Li et al. overview the breakthroughs in endothelial cell metabolism over the past decade and discusses possible therapeutic implications for stimulating or inhibiting vessel growth by manipulating endothelial cell metabolism.

Hallmarks of Endothelial Cell Metabolism in Health and Disease