OS9.1 Clinical significance of hypermutation in gliomas

Volume: 21, Issue: Supplement_3, Pages: iii18 - iii18
Published: Aug 1, 2019
Abstract
BACKGROUND Among patients with glioma, little is known about the clinical significance of hypermutation. We sought to define the determinants of hypermutation in gliomas, and to assess the value of this biomarker for predicting response to standard of care and immune checkpoint blockade. MATERIAL AND METHODS We performed comprehensive molecular characterization of 2420 pediatric and adult gliomas with clinical annotation. We determined the...
Paper Details
Title
OS9.1 Clinical significance of hypermutation in gliomas
Published Date
Aug 1, 2019
Journal
Volume
21
Issue
Supplement_3
Pages
iii18 - iii18
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