Quantifying the tradeoff between sequencing depth and cell number in single-cell RNA-seq
Abstract
The allocation of a sequencing budget when designing single cell RNA-seq experiments requires consideration of the tradeoff between number of cells sequenced and the read depth per cell. One approach to the problem is to perform a power analysis for a univariate objective such as differential expression. However, many of the goals of single-cell analysis requires consideration of the multivariate structure of gene expression, such as clustering....
Paper Details
Title
Quantifying the tradeoff between sequencing depth and cell number in single-cell RNA-seq
Published Date
Sep 9, 2019
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