Getting to the Cores of Autism
Abstract
The genetic architecture of autism spectrum disorder (ASD) is itself a diverse allelic spectrum that consists of rare de novo or inherited variants in hundreds of genes and common polygenic risk at thousands of loci. ASD susceptibility genes are interconnected at the level of transcriptional and protein networks, and many function as genetic regulators of neurodevelopment or synaptic proteins that regulate neural activity. So that the core...
Paper Details
Title
Getting to the Cores of Autism
Published Date
Sep 1, 2019
Journal
Volume
178
Issue
6
Pages
1287 - 1298
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Notes
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