Application of nanoencapsulated silymarin to improve its antioxidant and hepatoprotective activities against carbon tetrachloride-induced oxidative stress in broiler chickens

The objective of this study was to evaluate antioxidant and hepatoprotective activities of nanoencapsulated silymarin (NES) against carbon tetrachloride-induced oxidative stress in broiler chickens. An in vitro study was conducted using a 20 kHz ultrasound with 62.5% amplitude to produce NES, stabilized by alginate for controlled release of its bioactive compounds in simulated gastrointestinal tract of broiler chickens. Results showed that...