Functional Characterization of the Nemertide α Family of Peptide Toxins

Volume: 84, Issue: 8, Pages: 2121 - 2128
Published: Aug 16, 2021
Abstract
Peptide toxins find use in medicine, biotechnology, and agriculture. They are exploited as pharmaceutical tools, particularly for the investigation of ion channels. Here, we report the synthesis and activity of a novel family of peptide toxins: the cystine-knotted α nemertides. Following the prototypic α-1 and -2 (1 and 2), six more nemertides were discovered by mining of available nemertean transcriptomes. Here, we describe their synthesis...
Paper Details
Title
Functional Characterization of the Nemertide α Family of Peptide Toxins
Published Date
Aug 16, 2021
Volume
84
Issue
8
Pages
2121 - 2128
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