Development of Biarylalkyl Carboxylic Acid Amides with Improved Anti‐schistosomal Activity
Abstract
The parasitic disease schistosomiasis is the cause of more than 200 000 human deaths per year. Although the disease is treatable, there is one major shortcoming: praziquantel has been the only drug used to combat these parasites since 1977. The risk of the emergence of resistant schistosomes is known to be increasing, as a reduced sensitivity of these parasites toward praziquantel has been observed. We developed a new class of substances, which...
Paper Details
Title
Development of Biarylalkyl Carboxylic Acid Amides with Improved Anti‐schistosomal Activity
Published Date
Sep 18, 2019
Journal
Volume
14
Issue
21
Pages
1856 - 1862
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