Cell Clustering Promotes a Metabolic Switch that Supports Metastatic Colonization
Abstract
Cancer metastasis depends on cell survival following loss of extracellular matrix attachment and dissemination through the circulation. The metastatic spread can be enhanced by the clustering of detached cancer cells and increased antioxidant defense. Here, we link these responses by describing how cell clustering limits reactive oxygen species (ROS). Loss of attachment causes mitochondrial perturbations and increased ROS production. The...
Paper Details
Title
Cell Clustering Promotes a Metabolic Switch that Supports Metastatic Colonization
Published Date
Oct 1, 2019
Journal
Volume
30
Issue
4
Pages
720 - 734.e5
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History