Integrating Hi-C links with assembly graphs for chromosome-scale assembly.
Abstract
Long-read sequencing and novel long-range assays have revolutionized de novo genome assembly by automating the reconstruction of reference-quality genomes. In particular, Hi-C sequencing is becoming an economical method for generating chromosome-scale scaffolds. Despite its increasing popularity, there are limited open-source tools available. Errors, particularly inversions and fusions across chromosomes, remain higher than alternate scaffolding...
Paper Details
Title
Integrating Hi-C links with assembly graphs for chromosome-scale assembly.
Published Date
Aug 21, 2019
Journal
Volume
15
Issue
8
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Notes
History