Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties

Volume: 11, Issue: 8, Pages: 412 - 412
Published: Aug 13, 2019
Abstract
Retinal pigment epithelium (RPE) acts as an outer blood-retinal barrier that limits the access of circulating xenobiotics to the eye. In addition, the RPE limits posterior elimination of intravitreally injected drugs to circulation. Thus, permeation in the RPE has a significant effect on ocular pharmacokinetics. The RPE is also a potentially important drug target in age-related macular degeneration. Therefore, the cell models of the RPE are...
Paper Details
Title
Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties
Published Date
Aug 13, 2019
Volume
11
Issue
8
Pages
412 - 412
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