Protective effect of Ganoderma atrum polysaccharide on acrolein-induced macrophage injury via autophagy-dependent apoptosis pathway
Abstract
The study aimed to investigate the protective effect and underlying mechanism of Ganoderma atrum (G. atrum) polysaccharide (PSG-1) on macrophage injury induced by acrolein. The results showed that PSG-1 restored the cell viability damaged by acrolein. In addition, PSG-1 significantly reduced the acrolein-induced occurrence of apoptosis via increase of Bcl-2 expression, mitochondrial membrane potential (MMP), decrease of ROS, cytochrome c...
Paper Details
Title
Protective effect of Ganoderma atrum polysaccharide on acrolein-induced macrophage injury via autophagy-dependent apoptosis pathway
Published Date
Nov 1, 2019
Journal
Volume
133
Pages
110757 - 110757
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Notes
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