HIV-Associated Neurocognitive Disorders

Published on Jun 3, 2019
· DOI :10.1093/OXFORDHB/9780190664121.013.3
Jennifer E. Iudicello23
Estimated H-index: 23
(UCSD: University of California, San Diego),
Erin E. Morgan27
Estimated H-index: 27
(UCSD: University of California, San Diego)
+ 2 AuthorsRobert K. Heaton119
Estimated H-index: 119
(UCSD: University of California, San Diego)
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#3Ni Sun-Suslow (UCSD: University of California, San Diego)H-Index: 3
#4Suzi Hong (UCSD: University of California, San Diego)H-Index: 27
OBJECTIVE Recent cannabis exposure has been associated with lower rates of neurocognitive impairment in people with HIV (PWH). Cannabis's anti-inflammatory properties may underlie this relationship by reducing chronic neuroinflammation in PWH. This study examined relations between cannabis use and inflammatory biomarkers in cerebrospinal fluid (CSF) and plasma, and cognitive correlates of these biomarkers within a community-based sample of PWH. METHODS 263 individuals were categorized into four ...
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#1Laura M Campbell (UCSD: University of California, San Diego)H-Index: 7
#2Christine Fennema-Notestine (UCSD: University of California, San Diego)H-Index: 56
Last. Robert K. HeatonH-Index: 119
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Objective: Frascati international research criteria for HIV-associated neurocognitive disorders (HAND) are controversial; some investigators have argued that Frascati criteria are too liberal, resulting in a high false positive rate. Meyer et al. recommended more conservative revisions to HAND criteria, including exploring other commonly used methodologies for neurocognitive impairment (NCI) in HIV including the global deficit score (GDS). This study compares NCI classifications by Frascati, Mey...
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