Gastric environment-stable oral nanocarriers for in situ colorectal cancer therapy

Volume: 139, Pages: 1035 - 1045
Published: Oct 1, 2019
Abstract
Colorectal cancer (CRC) is a prevalent and fatal cancer. Oral administration provided the potential for in situ treatment of the colorectal cancer. However, drugs couldn't be well-absorbed mainly due to its degradation in the gastric area and poor intestinal permeability. In this study, we synthesized deoxycholic acid and hydroxybutyl decorated chitosan nanoparticles (DAHBC NPs) as oral curcumin (CUR) delivery system for colorectal cancer...
Paper Details
Title
Gastric environment-stable oral nanocarriers for in situ colorectal cancer therapy
Published Date
Oct 1, 2019
Volume
139
Pages
1035 - 1045
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