Microencapsulated islet-like microtissues with toroid geometry for enhanced cellular viability
Abstract
Transplantation of immuno-isolated islets is a promising strategy to restore insulin-secreting function in patients with Type 1 diabetes. However, the clinical translation of this treatment approach remains elusive due to the loss of islet viability resulting from hypoxia at the avascular transplantation site. To address this challenge, we designed non-spherical islet-like microtissues and investigated the effect of their geometries on cellular...
Paper Details
Title
Microencapsulated islet-like microtissues with toroid geometry for enhanced cellular viability
Published Date
Oct 1, 2019
Journal
Volume
97
Pages
260 - 271
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Notes
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