Emerging concepts in pseudoenzyme classification, evolution, and signaling
Abstract
The 21st century is witnessing an explosive surge in our understanding of pseudoenzyme-driven regulatory mechanisms in biology. Pseudoenzymes are proteins that have sequence homology with enzyme families but that are proven or predicted to lack enzyme activity due to mutations in otherwise conserved catalytic amino acids. The best-studied pseudoenzymes are pseudokinases, although examples from other families are emerging at a rapid rate as...
Paper Details
Title
Emerging concepts in pseudoenzyme classification, evolution, and signaling
Published Date
Aug 13, 2019
Journal
Volume
12
Issue
594
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