Ribosomopathies: Old Concepts, New Controversies.
Abstract
Ribosomopathies are a diverse subset of diseases caused by reduced expression of, or mutations in, factors necessary for making ribosomes, the protein translation machinery in the cell. Despite the ubiquitous need for ribosomes in all cell types, ribosomopathies manifest with tissue-specific defects and sometimes increased cancer susceptibility, but few treatments target the underlying cause. By highlighting new research in the field, we review...
Paper Details
Title
Ribosomopathies: Old Concepts, New Controversies.
Published Date
Oct 1, 2019
Journal
Volume
35
Issue
10
Pages
754 - 767
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