information processing

spatial memory

place cells

Current Biology

•Egocentric boundary cells (EBCs) were described within the hippocampal region•Using a GLM, “Pure” EBCs were identified mainly in the POR•Conjunctive EBCs × HD cells were identified mainly in the PaS and MEC•HD cells may drive the transformation from egocentric to allocentric coordinates Navigation requires the integration of many sensory inputs to form a multi-modal cognitive map of the environment, which is believed to be implemented in the hippocampal region by spatially tuned cells [1O’Keefe J. Nadel L. The Hippocampus as a Cognitive Map. Oxford University, 1978Google Scholar, 2McNaughton B.L. Battaglia F.P. Jensen O. Moser E.I. Moser M.B. Path integration and the neural basis of the ‘cognitive map’.Nat. Rev. Neurosci. 2006; 7: 663-678Crossref PubMed Scopus (1285) Google Scholar, 3Derdikman D. Moser E.I. A manifold of spatial maps in the brain.Trends Cogn. Sci. 2010; 14: 561-569Abstract Full Text Full Text PDF PubMed Scopus (133) Google Scholar, 4O’Keefe J. Dostrovsky J. The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat.Brain Res. 1971; 34: 171-175Crossref PubMed Scopus (3810) Google Scholar, 5Taube J.S. Muller R.U. Ranck Jr., J.B. Head-direction cells recorded from the postsubiculum in freely moving rats. I. Description and quantitative analysis.J. Neurosci. 1990; 10: 420-435Crossref PubMed Google Scholar, 6Derdikman D. Knierim J.J. Space, Time and Memory in the Hippocampal Formation. Springer, 2014Crossref Scopus (12) Google Scholar, 7Hafting T. Fyhn M. Molden S. Moser M.B. Moser E.I. Microstructure of a spatial map in the entorhinal cortex.Nature. 2005; 436: 801-806Crossref PubMed Scopus (2432) Google Scholar, 8Solstad T. Boccara C.N. Kropff E. Moser M.B. Moser E.I. Representation of geometric borders in the entorhinal cortex.Science. 2008; 322: 1865-1868Crossref PubMed Scopus (693) Google Scholar, 9Lever C. Burton S. Jeewajee A. O’Keefe J. Burgess N. Boundary vector cells in the subiculum of the hippocampal formation.J. Neurosci. 2009; 29: 9771-9777Crossref...

Dissociation between Postrhinal Cortex and Downstream Parahippocampal Regions in the Representation of Egocentric Boundaries