Characterization of lower limb muscle activation patterns during walking and running with Intravoxel Incoherent Motion (IVIM) MR perfusion imaging

The distribution of energy use among different lower limb muscles during walking and running is not well understood. Local blood flow within skeletal muscle tissue depends on its metabolic activity during activation. The non-invasive magnetic resonance microvascular perfusion method Intravoxel Incoherent Motion (IVIM) is able to quantify muscle activation. To non-invasively determine quantitative changes in local microvascular perfusion and...