Unilateral nipple hyperkeratosis

A 63-year-old man with a medical history significant for gynecomastia presented with concern of a new mole on the right nipple, present for approximately 1 year. The patient reported breast fullness and tenderness along with growth of the lesion without nipple discharge. Physical examination found a hyperkeratotic right nipple overlying a tender and indurated erythematous plaque with nipple retraction (Fig 1, A and B) compared with the...