Wingless‐type MMTV integration site family member 5a is a key inhibitor of islet stellate cells activation

Aims/Introduction Type 2 diabetes mellitus is a chronic metabolic disorder characterized by islet β‐cell dysfunction, which might result from the activation of islet stellate cells ( ISC s). Our recent study showed that a specific population of ISC s is prone to be activated in type 2 diabetes mellitus accompanied by reduced secretion of insulin. The wingless‐type MMTV integration site family member 5a (Wnt5a)/frizzled‐5 signaling pathway might...